Pay in 4 interest-free payments of $12.25 Learn more
Ships within 48 hours · Estimated delivery Jul 27 - Aug 1
PluriSIn-1 was identified by a high-throughput screening against undifferentiated human ESCs
It inhibits PHD2 with an IC50 ~21 nM
5-dimethylphenyl)-1H-benzo[d]imidazole-5-carboxamide
In cellular assays ML141 inhibited Cdc42-related filopodia formation and cell migration
Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment
ADC Toxin Monomethyl auristatin E (MMAE) - CAS# 474645-27-7 60023 PluriSIn-1 was identified by aMonomethyl auristatin E (MMAE, vedotin), CAS No. 474645 27 7, is a very potent anti mitotic agent that inhibits cell division by blocking the polymerisation of tubulin. Because of ts super toxicity, it cannot be used as a drug itself. In recent cancer therapy developments, it is linked to a monoclonal antibody (mAb) that recognizes a pecific marker expression in cancer cells and directs MMAE to the cancer cells. The linker linking MMAE to the
US$ 5995.00
US$ 6745.00
US$ 6745.00
US$ 7245.00
US$ 6745.00
US$ 262.50
US$ 6995.00
US$ 185.90
US$ 8245.00