Thalidomide-Propargyne-PEG2-COOH lafenamide hemifumarate It was approved by the

It was approved by the Food and Drug Administration (FDA) on June 23

durable tumor regression

with an IC50 of >200 μM

Smiles: CC(C)C1=CC=CC=C1CC1=CC(C(=O)NC2C=CC(=CC=2)S(=O)(=O)C2=CC=CC=C2C(C)(C)C)=C(O)C(O)=C1O

AFN-12520000

Thalidomide-Propargyne-PEG2-COOH lafenamide hemifumarate It was approved by theThalidomide Propargyne PEG2 COOH is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 428. 39 Formula: C21H20N2O8 Chemical Name: 3 [2 ({3 [2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 5 yl]prop 2 yn 1 yl}oxy)ethoxy]propanoic acid Smiles: OC(=O)CCOCCOCC#CC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O