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RO2959 monohydrochloride Size:2mg solid CAS Number: 147657-22-5

SKU: 28216113111

4.4
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Description

CAS Number: 147657-22-5

is a novel selective

the active principle within the extract of Penicillium aquamarinium

CAS Number: 10030-85-0

1–10 μM)

RO2959 monohydrochloride Size:2mg solid CAS Number: 147657-22-5RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1 Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL 2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. Product information CAS Number: 2309172 44 7

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