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WWL113 was administered by oral dosing once a day at a dose of 30-50 mg/kg in the model of diet-induced obesity ordb/db mice
Smiles: CC1C=CC(=CC=1)N1N=C(C=C1NC(=O)NC1C=CC(=CC=1)OCCN1CCOCC1)C(C)(C)C
and potently inhibits IRE1α RNase activity against XBP1 and Ins2 RNAs
Pickens LB
InChi: InChI=1S/C30H43FN4O11/c1-6-17(2)25(35-30(43)46-16-19-10-8-7-9-11-19)28(41)32-20(12-13-23(38)44-4)27(40)34-26(18(3)36)29(42)33-21(22(37)15-31)14-24(39)45-5/h7-11
Trimetazidine-N-oxide Catalog No.:M28034-C WWL113 was administered by oralTrimetazidine N oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3 ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti oxidant, anti inflammatory, antinociceptive and gastroprotective properties. Product information CAS Number: 1644530 89 1 Molecular Weight: 282. 34 Formula: C14H22N2O4 Chemical Name: 4 [(2,3,4
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