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Esculin Catalog No.:M12268-10 Chemical Name: methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidin-2-yl}amino)propan-2-yl]carbamate

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Description

Chemical Name: methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidin-2-yl}amino)propan-2-yl]carbamate

The ligand folds into itself to allow formation of specific intermolecular interactions in the ternary complex

bronchorelaxation and reduction of inflammation in asthma therapy

Both AUC and Cmax values are dose proportional for VX-702

which also contributes to AT7519 induced apoptosis independent of the inhibition of transcription

Esculin Catalog No.:M12268-10 Chemical Name: methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidin-2-yl}amino)propan-2-yl]carbamateEsculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts antioxidative stress and antiinflammatory effects, via the MAPK signaling pathway. Product information CAS Number: 531 75 9 Molecular Weight: 340. 28 Formula: C15H16O9 Chemical Name: 7 hydroxy 6 {[(2S, 3R, 4S, 5S, 6R) 3, 4, 5 trihydroxy 6 (hydroxymethyl)oxan 2 yl]oxy} 2H chromen

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