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m-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
22(4):537-50
and strains of Haemophilus and Listeria at concentrations of less than 3
6 hours) shows targeted downregulation of MCL-1 in both ABC and GCB subtypes
23)14(20)10-11
PF-3450074 60276 m-PEG3-SH is a PEG-based PROTACPF 3450074 (PF 74) is a specifical inhibitor of HIV 1 capsid protein (CA) and displays a broad spectrum inhibition of HIV isolates with submicromolar potency (EC50=8 640 nM). PF 3450074 (PF 74) acts at an early stage of HIV 1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. CPSF6: nuclear host factors
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